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Meta-analysis of preoperative surgical skin preparation with CHA vs PI was .. Chlorhexidine-alcohol versus povidone-iodine for surgical-site antisepsis. PDF | Since the patient’s skin is a major source of pathogens that cause surgical- site infection, optimization of preoperative skin antisepsis may. Chlorhexidine–Alcohol versus Povidone–Iodine for Surgical-Site Antisepsis. Article in Yearbook of Vascular Surgery · January with 21 Reads.

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Analyses comparing the antimicrobial activity and safety of current antiseptics: Efficacy of surgical preparation solutions in shoulder surgery. Chlorhexidine gluconate versus povidone iodine at cesarean delivery: Chlorhexidine-alcohol was significantly more protective than povidone-iodine against both superficial incisional infections 4.

Since the patient’s skin is a major source of pathogens that cause surgical-site infection, optimization of preoperative skin antisepsis may decrease postoperative infections. User Username Password Remember me. Guideline for prevention of surgical site infection, Chlorhexidine-alcohol versus povidone-iodine as preoperative skin preparation to prevent surgical site infection: The evidence of heterogeneity and publication bias was also assessed.

Secondary outcomes included individual types of surgical-site infections. Related Items Author’s work. Author’s work Hide Show all.

Chlorhexidine-Alcohol versus Povidone-Iodine for Surgical-Site Antisepsis.

WHO guidelines on hand hygiene in health care: Included studies were RCTs with the year of publication up to which compared the use povidone-iodlne chlorhexidine-alcohol versus povidone-iodine in its effectiveness reducing surgical site infection in adult patients.


The overall rate of surgical-site infection was significantly lower in the chlorhexidine-alcohol group than in the povidone-iodine group 9.

Antiseptic effectiveness with fibroblast preservation. A total of subjects in the chlorhexidine-alcohol group and in the povidone-iodine group qualified for the intention-to-treat analysis. Keywords chlorhexidine-alcohol; povidone-iodine; skin antisepsis; surgical site infection. J Am Coll Surg.

Comment in J Am Coll Surg. Systematic review and cost analysis comparing use of chlorhexidine with use of iodine for preoperative skin antisepsis to prevent surgical site infection. N Engl J Med. Article Tools Print this article. The literature search was conducted through the PubMed database on November The primary outcome was any surgical-site infection within 30 days after surgery. Comparison of the efficacy of chlorhexidine gluconate versus povidone iodine as preoperative skin preparation for the prevention of surgical site infections in clean-contaminated upper abdominal surgeries.

Similar results were observed in the per-protocol analysis of the patients who remained in the study during the day follow-up period. Email this article Login required.

Chlorhexidine–pharmacology and clinical applications. We hypothesized that preoperative skin cleansing with chlorhexidine-alcohol is more protective against infection than is povidone-iodine. Preoperative cleansing of the patient’s skin with chlorhexidine-alcohol is superior to cleansing with povidone-iodine for preventing surgical-site infection after clean-contaminated surgery.


Six RCTs with a total of 2, patients were included in the meta-analysis.

Hospital infection control practices advisory committee. Spine Phila Pa Review Manager RevMan [Computer program]. DuraPrep surgical solution iodine povacrylex [0. How to cite item.

Guidelines for the prevention of intravascular catheter-related infections. A meta-analysis was conducted in the included study to obtain chlorhexidine–alcohol pooled estimate of the effect size. Infect Control Hosp Epidemiol.

Chlorhexidine-Alcohol versus Povidone-Iodine for Surgical-Site Antisepsis.

A comparison of chlorhexidine-alcohol versus povidone-iodine for eliminating skin flora before genitourinary prosthetic surgery: This study aims to compare the chloorhexidine-alcohol of chlorhexidine-alcohol versus povidone-iodine for preoperative skin preparation to prevent surgical site infection.

Adverse events were similar in the two study groups. Surgical site infection remains substantial problems to surgeons and patients as it increases the morbidity, mortality, length of stay, hospital cost, rate of re-admission, and rate of re-surgery.


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