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Histoid leprosy is a skin condition, a rare form of multibacillary leprosy See also[edit]. Leprosy · Skin lesion. References[edit]. ^ James, William D.; Berger. Histoid leprosy, an uncommon variant of lepromatous leprosy, develops usually as relapse in lepromatous patients who are on dapsone. Summary Histoid leprosy is a rare multibacillary form that presents with disseminated papule-nodular cutaneous lesions. To study the inflammatory infiltrate.

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Actinomycetaceae Actinomyces israelii Actinomycosis Cutaneous actinomycosis Tropheryma whipplei Whipple’s disease Arcanobacterium haemolyticum Arcanobacterium haemolyticum infection Actinomyces gerencseriae.

A retrospective study of 40 cases from India. How to cite this article: Early diagnosis and management of these cases are important in this era of leprosy eradication. The ulnar nerve has been reported as the commonest nerve involved [ 4 ].

Histoid leprosy is an uncommon variant of lepromatous leprosy with characteristic clinical, immunologic, and bacteriologic findings. Clinical examination revealed multiple discrete, skin-colored, shiny cutaneous and subcutaneous nodules over the trunk and limbs. Reports are available with pronounced involvement of the face, the ears may show little change or may be unaffected [ 15 ].

In such cases, histoid lesions are transient because the histoid bacilli and the dapsone susceptible M. There was no history of fever, pain, epistaxis, pedal edema, altered sensations or long-term drug intake for the same. This article has been cited by.


This rare form of the disease, with unique clinical and histopathological features, may pose a diagnostic challenge even to astute clinicians. Actinobacteria primarily A00—A79—, — Histoid leprosy is considered a variant of lepromatous leprosy[ 2 ] and by others as a distinct entity.

Palit A, Inamadar AC. J Indian Soc Teledermatol. How to cite this URL: The AFB are not found in globi formation, as they do not secrete any glial substance. Early diagnosis and complete treatment is very important to achieve our goal of elimination of leprosy.

Lepromatous leprosy of histoid type Annigeri S R, Metgud S C, Patil J R – Indian J Med Microbiol

Fite’s stain from FNAC is also positive in case of histoid leprosy, which must stimulate interest for further studies. A histopathological examination of the skin lesion was ordered which revealed sheets of histiocytes and lepra bacilli on hematoxylin and eosin and acid fast staining.

Histopathology of the lower back nodule showed atrophic epidermis with a subepidermal grenz zone. The aetiopathogenesis of this entity is not clear but an increased cell-mediated CM and humoral immunity against M.

Table of Contents Alerts. Arch Argent Dermatol ; However, it has also been reported in patients who relapsed even on supervised monthly dose of multidrug therapy and in patients without any treatment [ 3 ]. Adriano Piris, Alice Z.


No family history and contact history with known case of leprosy.

Case Reports in Pathology

Lepromatous leprosy of histoid type: Multiple, well-defined, erythematous nodules and papules present over the back and neck Click here to view. Histoid variety of lepromatous leprosy.

Lepromatous leprosy of histoid type. Fine needle aspiration hisgoid, histoid Hansen, lepromatous leprosy. How to cite this URL: Evolution of histoid leprosy de novo in lepromatous multibacillary leprosy.

It is a variant of lepromatous leprosy. No history of epistaxis and pedal edema.

Histoid leprosy

Indian J Dermatol Venerol Leprol. Indian J Med Microbiol. Hematological findings were normal except for mild histoiv. Histopathological differentials include dermatofibromas and neurofibromas and fibrohistiocytoma. Fine needle aspiratin cytology in leprosy.

Histoid leprosy Histoid leprosy is a skin condition, a rare form of multibacillary leprosy. This infection-related cutaneous condition article is a stub.


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